INTRACRANIAL VASOSPASM
\ˌɪntɹəkɹˈe͡ɪnɪəl vˈasəspˌazəm], \ˌɪntɹəkɹˈeɪnɪəl vˈasəspˌazəm], \ˌɪ_n_t_ɹ_ə_k_ɹ_ˈeɪ_n_ɪ__ə_l v_ˈa_s_ə_s_p_ˌa_z_ə_m]\
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Narrowing of the lumen of one or more intracranial arteries due to contraction of arterial smooth muscle or to morphologic changes of the blood vessel wall. Large blood vessels near the base of the brain are primarily affected and reduced blood flow may result in hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN). Vasospasm may be associated with SUBARACHNOID HEMORRHAGE; CRANIOCEREBRAL TRAUMA; and other disorders. (From Neurosurg Clin N Am, 1998 Jul;9 (3):615-27)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.