HELIX TURN HELIX MOTIFS
\hˈiːlɪks tˈɜːn hˈiːlɪks mə͡ʊtˈiːfs], \hˈiːlɪks tˈɜːn hˈiːlɪks məʊtˈiːfs], \h_ˈiː_l_ɪ_k_s t_ˈɜː_n h_ˈiː_l_ɪ_k_s m_əʊ_t_ˈiː_f_s]\
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The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)
By DataStellar Co., Ltd
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Nearby Words
- helix hortensis
- helix loop helix motif
- helix loop helix motifs
- helix pomatia
- helix turn helix motif
- Helix Turn Helix Motifs
- helixes
- helkai
- hell
- hell dust
- hell hound