HELIX TURN HELIX MOTIF
\hˈiːlɪks tˈɜːn hˈiːlɪks mə͡ʊtˈiːf], \hˈiːlɪks tˈɜːn hˈiːlɪks məʊtˈiːf], \h_ˈiː_l_ɪ_k_s t_ˈɜː_n h_ˈiː_l_ɪ_k_s m_əʊ_t_ˈiː_f]\
Sort: Oldest first
-
The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)
By DataStellar Co., Ltd
Word of the day
Snake's-head
- Guinea-hen flower; -- so called in England because its spotted petals resemble the scales of a snake's head.