GHON'S PRIMARY LESION

\ɡˈɒnz pɹˈa͡ɪməɹi lˈiːʒən], \ɡˈɒnz pɹˈa‍ɪməɹi lˈiːʒən], \ɡ_ˈɒ_n_z p_ɹ_ˈaɪ_m_ə_ɹ_i l_ˈiː_ʒ_ə_n]\

Definitions of GHON'S PRIMARY LESION

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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