GHILARDUCCI'S REACTION

\ɡˈɪlɑːdˌuːt͡ʃa͡ɪz ɹɪˈakʃən], \ɡˈɪlɑːdˌuːt‍ʃa‍ɪz ɹɪˈakʃən], \ɡ_ˈɪ_l_ɑː_d_ˌuː_tʃ_aɪ_z ɹ_ɪ__ˈa_k_ʃ_ə_n]\

Definitions of GHILARDUCCI'S REACTION

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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