WATERHOUSE FRIEDERICHSEN SYNDROME

\wˈɔːtəhˌa͡ʊs fɹˈiːdɪɹˌɪt͡ʃsən sˈɪndɹə͡ʊm], \wˈɔːtəhˌa‍ʊs fɹˈiːdɪɹˌɪt‍ʃsən sˈɪndɹə‍ʊm], \w_ˈɔː_t_ə_h_ˌaʊ_s f_ɹ_ˈiː_d_ɪ_ɹ_ˌɪ_tʃ_s_ə_n s_ˈɪ_n_d_ɹ_əʊ_m]\

Definitions of WATERHOUSE FRIEDERICHSEN SYNDROME

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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