WATERHOUSE FRIDERICHSEN SYNDROME

\wˈɔːtəhˌa͡ʊs fɹˈa͡ɪdɹɪt͡ʃsən sˈɪndɹə͡ʊm], \wˈɔːtəhˌa‍ʊs fɹˈa‍ɪdɹɪt‍ʃsən sˈɪndɹə‍ʊm], \w_ˈɔː_t_ə_h_ˌaʊ_s f_ɹ_ˈaɪ_d_ɹ_ɪ_tʃ_s_ə_n s_ˈɪ_n_d_ɹ_əʊ_m]\
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2010 - Medical Dictionary Database
By DataStellar Co., Ltd

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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