VOGT'S POINT

\vˈɒɡts pˈɔ͡ɪnt], \vˈɒɡts pˈɔ‍ɪnt], \v_ˈɒ_ɡ_t_s p_ˈɔɪ_n_t]\

Definitions of VOGT'S POINT

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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