SOLAR AGING OF SKIN
\sˈə͡ʊləɹ ˈe͡ɪd͡ʒɪŋ ɒv skˈɪn], \sˈəʊləɹ ˈeɪdʒɪŋ ɒv skˈɪn], \s_ˈəʊ_l_ə_ɹ ˈeɪ_dʒ_ɪ_ŋ ɒ_v s_k_ˈɪ_n]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.