SIGMASPIRE
\sˈɪɡmaspˌa͡ɪ͡ə], \sˈɪɡmaspˌaɪə], \s_ˈɪ_ɡ_m_a_s_p_ˌaɪə]\
Definitions of SIGMASPIRE
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.