RATHKE'S COLUMNS

\ɹˈaθks kˈɒlʌmz], \ɹˈaθks kˈɒlʌmz], \ɹ_ˈa_θ_k_s k_ˈɒ_l_ʌ_m_z]\

Definitions of RATHKE'S COLUMNS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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