PORTIO WRISBERGII

\pˈɔːtɪˌə͡ʊ ɹˈɪsbəd͡ʒˌɪa͡ɪ], \pˈɔːtɪˌə‍ʊ ɹˈɪsbəd‍ʒˌɪa‍ɪ], \p_ˈɔː_t_ɪ__ˌəʊ ɹ_ˈɪ_s_b_ə_dʒ_ˌɪ__aɪ]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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