PL97 248

\pˌiːˈɛl nˈa͡ɪntisˈɛvən tˈuːhˈʌndɹədən fˈɔːtiˈe͡ɪt], \pˌiːˈɛl nˈa‍ɪntisˈɛvən tˈuːhˈʌndɹədən fˈɔːtiˈe‍ɪt], \p_ˌiː__ˈɛ_l n_ˈaɪ_n_t_i_s_ˈɛ_v_ə_n t_ˈuː_h_ˈʌ_n_d_ɹ_ə_d_ə_n f_ˈɔː_t_i__ˈeɪ_t]\

Definitions of PL97 248

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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