NORWALK AGENT
\nˈɔːwɔːk ˈe͡ɪd͡ʒənt], \nˈɔːwɔːk ˈeɪdʒənt], \n_ˈɔː_w_ɔː_k ˈeɪ_dʒ_ə_n_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.