METHISOPRINOL
\mˈɛθɪsˌɒpɹɪnˌɒl], \mˈɛθɪsˌɒpɹɪnˌɒl], \m_ˈɛ_θ_ɪ_s_ˌɒ_p_ɹ_ɪ_n_ˌɒ_l]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.