MALICE PREPENSE
\mˈalɪs pɹɪpˈɛns], \mˈalɪs pɹɪpˈɛns], \m_ˈa_l_ɪ_s p_ɹ_ɪ_p_ˈɛ_n_s]\
Definitions of MALICE PREPENSE
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.