LIVE AXLE
\lˈa͡ɪv ˈaksə͡l], \lˈaɪv ˈaksəl], \l_ˈaɪ_v ˈa_k_s_əl]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.