ISOASPARTATE
\ˈa͡ɪsə͡ʊspˌɑːte͡ɪt], \ˈaɪsəʊspˌɑːteɪt], \ˈaɪ_s_əʊ_s_p_ˌɑː_t_eɪ_t]\
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An ASPARTIC ACID residue in polypeptide chains that is linked at the beta-carboxyl group instead of at the normal, alpha-carboxyl group, polypeptide linkage. It is a result of the spontaneous decomposition of aspartic acid or ASPARAGINE residues.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.