HYDROCHLORATE

\hˈa͡ɪdɹəklˌɔːɹe͡ɪt], \hˈa‍ɪdɹəklˌɔːɹe‍ɪt], \h_ˈaɪ_d_ɹ_ə_k_l_ˌɔː_ɹ_eɪ_t]\

Definitions of HYDROCHLORATE

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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