HETEROTYPIC ANTIBODIES
\hˌɛtɹə͡ʊtˈɪpɪk ˈantɪbˌɒdɪz], \hˌɛtɹəʊtˈɪpɪk ˈantɪbˌɒdɪz], \h_ˌɛ_t_ɹ_əʊ_t_ˈɪ_p_ɪ_k ˈa_n_t_ɪ_b_ˌɒ_d_ɪ_z]\
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Antibodies elicited in a different species from which the antigen originated. These antibodies are directed against a wide variety of interspecies-specific antigens, the best known of which are Forssman, Hanganutziu-Deicher (H-D), and Paul-Bunnell (P-B). Incidence of antibodies to these antigens--i.e., the phenomenon of heterophile antibody response--is useful in the serodiagnosis, pathogenesis, and prognosis of infection and latent infectious states as well as in cancer classification.
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