ERYTHRONIUM AMERICANUM, E.
\ˌɜːɹɪθɹˈə͡ʊni͡əm ɐmˈɛɹɪkˌanəm], \ˌɜːɹɪθɹˈəʊniəm ɐmˈɛɹɪkˌanəm], \ˌɜː_ɹ_ɪ_θ_ɹ_ˈəʊ_n_iə_m ɐ_m_ˈɛ_ɹ_ɪ_k_ˌa_n_ə_m]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.