ENGELMANN'S DISCS

\ɛnd͡ʒˈɛlmanz dˈɪsks], \ɛnd‍ʒˈɛlmanz dˈɪsks], \ɛ_n_dʒ_ˈɛ_l_m_a_n_z d_ˈɪ_s_k_s]\

Definitions of ENGELMANN'S DISCS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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