DUTCH CLINKERS
\dˈʌt͡ʃ klˈɪŋkəz], \dˈʌtʃ klˈɪŋkəz], \d_ˈʌ_tʃ k_l_ˈɪ_ŋ_k_ə_z]\
Definitions of DUTCH CLINKERS
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.