DESIGNATIO

\dˌɛzɪɡnˈe͡ɪʃɪˌə͡ʊ], \dˌɛzɪɡnˈe‍ɪʃɪˌə‍ʊ], \d_ˌɛ_z_ɪ_ɡ_n_ˈeɪ_ʃ_ɪ__ˌəʊ]\

Definitions of DESIGNATIO

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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