DESCRIPTION OF

\dɪskɹˈɪpʃən ɒv], \dɪskɹˈɪpʃən ɒv], \d_ɪ_s_k_ɹ_ˈɪ_p_ʃ_ə_n ɒ_v]\

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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