CRAMP BONE

\kɹˈamp bˈə͡ʊn], \kɹˈamp bˈə‍ʊn], \k_ɹ_ˈa_m_p b_ˈəʊ_n]\

Definitions of CRAMP BONE

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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