CONTEMPLANCE
\kˈɒntɛmpləns], \kˈɒntɛmpləns], \k_ˈɒ_n_t_ɛ_m_p_l_ə_n_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.