COLLAMER, JACOB

\kˈɒle͡ɪmə], \kˈɒle‍ɪmə], \k_ˈɒ_l_eɪ_m_ə]\

Definitions of COLLAMER, JACOB

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1894 - Dictionary of United States history
By John Franklin Jameson

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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