BRETONNEAU'S METHOD

\bɹˈɛtənˌə͡ʊz mˈɛθəd], \bɹˈɛtənˌə‍ʊz mˈɛθəd], \b_ɹ_ˈɛ_t_ə_n_ˌəʊ_z m_ˈɛ_θ_ə_d]\

Definitions of BRETONNEAU'S METHOD

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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