ANTIRABIC VACCINATION
\ˌantɪɹˈabɪk vˌaksɪnˈe͡ɪʃən], \ˌantɪɹˈabɪk vˌaksɪnˈeɪʃən], \ˌa_n_t_ɪ_ɹ_ˈa_b_ɪ_k v_ˌa_k_s_ɪ_n_ˈeɪ_ʃ_ə_n]\
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Protective inoculation against rabies. The virus is inoculated from rabbit to rabbit until it attains its maximum virulence. This is known as fixed virus and kills a rabbit in about seven days after subdural inoculation. The spinal cord from a rabbit so killed is dried over sticks of caustic potash. At the end of fourteen days it is practically avirulent. A portion of this cord emulsified in saline solution forms the first injection. Successive injections are made with material from cords dried for shorter and shorter periods until fresh cord is used.
By Smith Ely Jelliffe
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.