ANCONEUS EXTERNUS

\ˈankə͡ʊnɪəs ɛkstˈɜːnəs], \ˈankə‍ʊnɪəs ɛkstˈɜːnəs], \ˈa_n_k_əʊ_n_ɪ__ə_s ɛ_k_s_t_ˈɜː_n_ə_s]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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