ALKALINE COMET ASSAY
\ˈalkəlˌa͡ɪn kˈɒmɪt ɐsˈe͡ɪ], \ˈalkəlˌaɪn kˈɒmɪt ɐsˈeɪ], \ˈa_l_k_ə_l_ˌaɪ_n k_ˈɒ_m_ɪ_t ɐ_s_ˈeɪ]\
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A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a "comet with tail" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.