VALENCE, VALENCY
\vˈe͡ɪləns], \vˈeɪləns], \v_ˈeɪ_l_ə_n_s]\
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The property possessed by an element or a radicle of uniting with the element hydrogen or replacing it in chemical compounds. If the element or radicle replaces or unites with only one hydrogen atom it is univalent; if two, bivalent; if three, trivalent, etc.
By Smith Ely Jelliffe
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.