TRIVAZOL
\tɹˈa͡ɪvɐzˌɒl], \tɹˈaɪvɐzˌɒl], \t_ɹ_ˈaɪ_v_ɐ_z_ˌɒ_l]\
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An antiprotozoal used in amebiasis, trichomoniasis, giardiasis, and as a treponemacide in livestock. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.