STIFF PUPIL

\stˈɪf pjˈuːpə͡l], \stˈɪf pjˈuːpə‍l], \s_t_ˈɪ_f p_j_ˈuː_p_əl]\

Definitions of STIFF PUPIL

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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