SOUTHERN ALPS
\sˈʌðən ˈalps], \sˈʌðən ˈalps], \s_ˈʌ_ð_ə_n ˈa_l_p_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.