RACHITIDES
\ɹˈat͡ʃɪtˌa͡ɪdz], \ɹˈatʃɪtˌaɪdz], \ɹ_ˈa_tʃ_ɪ_t_ˌaɪ_d_z]\
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A condition caused by deficiency of VITAMIN D, especially in infancy and childhood, with disturbance of normal ossification. The disease is marked by bending and distortion of the bones under muscular action, by the formation of nodular enlargements on the ends and sides of the bones, by delayed closure of the fontanels, pain in the muscles, and sweating of the head. Vitamin D and sunlight together with an adequate diet are curative, provided that the parathyroid glands are functioning properly. (Dorland, 27th ed)
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.