PANICOVIRUSES
\pˈanɪkˌɒva͡ɪɹəsɪz], \pˈanɪkˌɒvaɪɹəsɪz], \p_ˈa_n_ɪ_k_ˌɒ_v_aɪ_ɹ_ə_s_ɪ_z]\
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A family of RNA plant viruses infecting dicotyledons. Transmission is mainly by mechanical inoculation and through propagative plant material. All species elicit formation of multivesicular inclusion bodies. There are at least eight genera: Aureusvirus, Avenavirus, CARMOVIRUS, Dianthovirus, Machlomovirus, Necrovirus, Panicovirus, and TOMBUSVIRUS.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.