OBTRUSION

\ɒbtɹˈuːʒən], \ɒbtɹˈuːʒən], \ɒ_b_t_ɹ_ˈuː_ʒ_ə_n]\
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1919 - The Winston Simplified Dictionary
By William Dodge Lewis, Edgar Arthur Singer
 
1919 - The Concise Standard Dictionary of the English Language
By James Champlin Fernald
 
1871 - The Cabinet Dictionary of the English Language

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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