MRS ALEXANDER

\mˈɪsɪz ˌalɪɡzˈandə], \mˈɪsɪz ˌalɪɡzˈandə], \m_ˈɪ_s_ɪ_z ˌa_l_ɪ_ɡ_z_ˈa_n_d_ə]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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