MANN'S SIGN
\mˈanz sˈa͡ɪn], \mˈanz sˈaɪn], \m_ˈa_n_z s_ˈaɪ_n]\
Definitions of MANN'S SIGN
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.