MALIGNANT SYPHILIS
\məlˈɪɡnənt sˈɪfəlɪs], \məlˈɪɡnənt sˈɪfəlɪs], \m_ə_l_ˈɪ_ɡ_n_ə_n_t s_ˈɪ_f_ə_l_ɪ_s]\
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The occurrence of severe constitutional symptoms early in the secondary stage.
By Smith Ely Jelliffe
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.