LY 139037

\lˈa͡ɪ wˈɒnhˈʌndɹədən θˈɜːtinˈa͡ɪn θˈa͡ʊzənd ən θˈɜːtisˈɛvən], \lˈa‍ɪ wˈɒnhˈʌndɹədən θˈɜːtinˈa‍ɪn θˈa‍ʊzənd ən θˈɜːtisˈɛvən], \l_ˈaɪ w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n θ_ˈɜː_t_i_n_ˈaɪ_n θ_ˈaʊ_z_ə_n_d_ ə_n θ_ˈɜː_t_i_s_ˈɛ_v_ə_n]\

Definitions of LY 139037

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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