LOTIO ADSTRINGENS

\lˈə͡ʊtɪˌə͡ʊ ɐdstɹˈɪnd͡ʒənz], \lˈə‍ʊtɪˌə‍ʊ ɐdstɹˈɪnd‍ʒənz], \l_ˈəʊ_t_ɪ__ˌəʊ ɐ_d_s_t_ɹ_ˈɪ_n_dʒ_ə_n_z]\

Definitions of LOTIO ADSTRINGENS

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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