INTIMUM UNGUIS

\ɪntˈɪməm ˈʌnɡwiz], \ɪntˈɪməm ˈʌnɡwiz], \ɪ_n_t_ˈɪ_m_ə_m ˈʌ_n_ɡ_w_i_z]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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