INITIAL LESION (OF SYPHILIS)

\ɪnˈɪʃə͡l lˈiːʒən ɒv sˈɪfəlɪs], \ɪnˈɪʃə‍l lˈiːʒən ɒv sˈɪfəlɪs], \ɪ_n_ˈɪ_ʃ_əl l_ˈiː_ʒ_ə_n__ ɒ_v s_ˈɪ_f_ə_l_ɪ_s]\

Definitions of INITIAL LESION (OF SYPHILIS)

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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