IGOR YEVGENEEVICH TAMM
\ˈiːɡɔː jˈɛvd͡ʒənˌiːvɪt͡ʃ tˈam], \ˈiːɡɔː jˈɛvdʒənˌiːvɪtʃ tˈam], \ˈiː_ɡ_ɔː j_ˈɛ_v_dʒ_ə_n_ˌiː_v_ɪ_tʃ t_ˈa_m]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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