HALSTERN'S DISEASE

\hˈalstənz dɪzˈiːz], \hˈalstənz dɪzˈiːz], \h_ˈa_l_s_t_ə_n_z d_ɪ_z_ˈiː_z]\

Definitions of HALSTERN'S DISEASE

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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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