GIANOTTI CROSTI SYNDROME

\d͡ʒɐnˈɒti kɹˈɒsti sˈɪndɹə͡ʊm], \d‍ʒɐnˈɒti kɹˈɒsti sˈɪndɹə‍ʊm], \dʒ_ɐ_n_ˈɒ_t_i k_ɹ_ˈɒ_s_t_i s_ˈɪ_n_d_ɹ_əʊ_m]\

Definitions of GIANOTTI CROSTI SYNDROME

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2010 - Medical Dictionary Database
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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