GENERALIZED CONVULSIVE EPILEPSY
\d͡ʒˈɛnəɹə͡lˌa͡ɪzd kənvˈʌlsɪv ˈɛpɪlˌɛpsi], \dʒˈɛnəɹəlˌaɪzd kənvˈʌlsɪv ˈɛpɪlˌɛpsi], \dʒ_ˈɛ_n_ə_ɹ_əl_ˌaɪ_z_d k_ə_n_v_ˈʌ_l_s_ɪ_v ˈɛ_p_ɪ_l_ˌɛ_p_s_i]\
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Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71 (4):405-14)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.